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Salvianolic acid B inhibits Abeta fibril formation and disaggregates preformed fibrils and protects

School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China. One of the major pathological features of Alzheimer's disease (AD) is the appearance of senile plaques characterized by extracellular aggregation of amyloid beta-peptide (Abeta) fibrils. Inhibition of Abeta fibril aggregation is therefore viewed as one possible method to halt the progression of AD. Salvianolic acid B (Sal B) is an active ingredient isolated from Salvia miltiorrhiza, a Chinese herbal medici 
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martedì, 26 mag 2009 Ore. 04.09

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